Author

C. Ragulan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Sadanandam· 4 shared D. Cunningham· 2 shared G. Nyamundanda· 2 shared H. Ps· 2 shared K. Desai· 2 shared P. Poudel· 2 shared Y. Patil· 2 shared A. Andren· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCancer Biology

A. Sadanandam

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4 papers

Recent·Most cited

Context-specific GITR agonism potentiates anti-PD-L1 and CD40-based immuno- chemotherapy combination in heterogeneous pancreatic tumors

C. Ragulan, K. Desai, P. V. Lawrence, Y. Ikami, M. M. Aalam, H. Ps, N. Kannan, D. Cunningham, N. Starling, A. Sadanandam

This study identifies GITR agonism as a potential enhancer of anti-PD-L1 and CD40-based immunotherapy in pancreatic tumors by targeting immune evasion mechanisms.

bioRxiv · Jun 16, 2023 · PreprintCancer Biology

A comprehensive analysis of immune landscape of Indian triple negative breast cancer

A. Korlimarla, H. PS, J. Prabhu, C. Ragulan, Y. Patil, S. VP, K. Desai, A. Mathew, S. Appachu, R. Diwakar, S. BS, M. Cheang, A. Sadanandam

This study identifies three immune subtypes in Indian triple-negative breast cancer patients, showing similarities to Western TNBCs and potential for immunotherapy response.

bioRxiv · Mar 6, 2022 · PreprintCancer Biology

Nutrient profiling reveals extracellular uridine as a fuel for pancreatic cancer through uridine phosphorylase 1

M. H. Ward, Z. C. Nwosu, P. Poudel, S. Kasperek, Z. Tolstyka, R. E. Menjivar, C. Ragulan, G. Nyamundanda, L. Zhang, A. Andren, C. J. Halbrook, E. S. Carpenter, M. Pasca di Magliano, A. Sadanandam, C. A. Lyssiotis

This study identifies uridine as a novel nutrient for pancreatic cancer cells through uridine phosphorylase 1, showing its role in survival and metabolism under glucose deprivation.

bioRxiv · Jun 7, 2021 · PreprintCancer Biology

Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer Samples into Molecular Subtypes

C. Ragulan, K. Eason, G. Nyamundanda, Y. Patil, P. Poudel, E. Fontana, M. Del Rio, S.-L. Koo, W. S. Tan, P. Martineau, D. Cunningham, I. Tan, A. Sadanandam

The paper validates a NanoString-based biomarker assay for classifying colorectal cancer samples into molecular subtypes with high concordance across platforms and tissue types.

bioRxiv · Apr 12, 2018Cancer Biology