Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct
y. SIMONI, S. LI, S. ZHUANG, A. HEIT, S.-L. KOO, I.-T. CHOW, W. W. KWOK, I. B. TAN, D. S. W. TAN, E. W. NEWELL
The paper identifies bystander CD4+ T cells in human tumors, showing they are phenotypically distinct and express CD39, correlating with CD8+ TILs specific for non-cancer antigens.
bioRxiv · Jul 15, 2020 · PreprintImmunology