Author

C. Roecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Sefer· 1 shared D. Neuhaus· 1 shared E. Kallis· 1 shared J. Michaelis· 1 shared S. Eustermann· 1 shared T. Eilert· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

A. Sefer

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1 paper

Recent·Most cited

Structural dynamics of DNA strand break sensing by PARP-1 at a single-molecule level

A. Sefer, E. Kallis, T. Eilert, C. Roecker, D. Neuhaus, S. Eustermann, J. Michaelis

This study investigates how PARP-1 senses DNA single-strand breaks at the single-molecule level, revealing an induced fit mechanism involving multi-domain assembly and inhibitor effects.

bioRxiv · Feb 26, 2022Biophysics