Author

S. Eustermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 5 Approach:experimental assay· 5 Assay:DNA methylation· 3 Organism:yeast· 3 Assay:ChIP-seq· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

K.-P. Hopfner· 3 shared E. Oberbeckmann· 2 shared M. Moldt· 2 shared P. Korber· 2 shared V. Niebauer· 2 shared A. Basu· 1 shared A. Ranjan· 1 shared A. Schmid· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

K.-P. Hopfner

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Author profile →

5 papers

Recent·Most cited

Structural dynamics of DNA strand break sensing by PARP-1 at a single-molecule level

A. Sefer, E. Kallis, T. Eilert, C. Roecker, D. Neuhaus, S. Eustermann, J. Michaelis

This study investigates how PARP-1 senses DNA single-strand breaks at the single-molecule level, revealing an induced fit mechanism involving multi-domain assembly and inhibitor effects.

bioRxiv · Feb 26, 2022Biophysics

A hold-and-feed mechanism drives directional DNA loop extrusion by condensin

I. A. Shaltiel, S. Datta, L. Lecomte, M. Hassler, M. Kschonsak, S. Bravo, C. Stober, S. Eustermann, C. H. Haering

This study reveals that condensin uses a hold-and-feed mechanism to extrude DNA loops bidirectionally by separating motor and anchor functions in distinct chambers.

bioRxiv · Oct 29, 2021Biochemistry

Genome information processing by the INO80 chromatin remodeler positions nucleosomes

E. Oberbeckmann, N. Krietenstein, V. Niebauer, Y. Wang, K. Schall, M. Moldt, T. Straub, R. Rohs, K.-P. Hopfner, P. Korber, S. Eustermann

This study identifies DNA shape/mechanics as key determinants for nucleosome positioning by the INO80 chromatin remodeler in yeast.

bioRxiv · Nov 3, 2020Biochemistry

Measuring DNA mechanics on the genome scale

A. Basu, D. G. Bobrovnikov, Z. Qureshi, T. Kayikcioglu, T. T. Ngo, A. Ranjan, S. Eustermann, B. Cieza, M. Hejna, T. H. Rube, K.-P. Hopfner, C. Wolberger, J. S. Song, T. Ha

This paper develops loop-seq to measure DNA bendability genome-wide and finds sequence-encoded low bendability upstream of TSSs that influences nucleosome positioning and chromatin remodeling.

bioRxiv · Aug 17, 2020Biophysics

Ruler elements in chromatin remodelers set nucleosome array spacing and phasing

E. Oberbeckmann, V. Niebauer, S. Watanabe, L. Farnung, M. Moldt, A. Schmid, P. Cramer, C. L. Peterson, S. Eustermann, K.-P. Hopfner, P. Korber

The paper identifies a ruler element in chromatin remodelers that determines nucleosome spacing and phasing in Saccharomyces cerevisiae.

bioRxiv · Feb 28, 2020Biochemistry