Author

C. Savy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Carminati· 1 shared A. Jacquel· 1 shared A. Porterszman· 1 shared A. R. Martin· 1 shared A. Vigroux· 1 shared C. Birck· 1 shared C. Bontoux· 1 shared C. Favreau· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Carminati

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Disrupting USP39 deubiquitinase Function Impairs the Survival and Migration of Multiple Myeloma Cells through ZEB1 Degradation

J. Sirera, S. Sarlak, M. Teisseire, A. Carminati, C. Savy, V. Nicolini, P. Brest, C. Bontoux, M. Deckert, M. Ohanna, S. GIULIANO, M. Dufies, G. Pages, F. Luciano

This study identifies USP39 as a critical survival and migration factor in multiple myeloma cells, showing that its disruption leads to ZEB1 degradation and reduced tumor growth.

bioRxiv · Apr 23, 2024 · PreprintCancer Biology

Dual targeting of GPX4 and TXNRD1 triggers eradication of AML cells through induction of apoptosis and ferroptosis

C. Favreau, C. Savy, M. Bourgoin, T. Botton, S. Bailly, F. Granger, C. Birck, M. Zerhouni, E. Kerreneur, A. Vigroux, J. Dussart-Gautheret, M.-L. Arcangeli, T. Cluzeau, A. Porterszman, S. Rocchi, , G. Robert

The paper identifies two compounds that target GPX4 and TXNRD1 to induce apoptosis and ferroptosis in AML cells, effectively eradicating malignant cells while sparing normal hematopoietic cells.

bioRxiv · Apr 3, 2024 · PreprintBiochemistry