Author

C. Schinner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

M.-T. Wanuske· 4 shared V. Spindler· 4 shared C. Stüdle· 3 shared A. Zimmermann· 2 shared F. Vielmuth· 2 shared H. Franz· 2 shared J. Waschke· 2 shared M. Hiermaier· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

M.-T. Wanuske

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Author profile →

4 papers

Recent·Most cited

Desmosomal cell cohesion and epidermal differentiation are modulated by dolichol phosphate mannosyltransferase 1 (DPM1) through SERPINB5-dependent mechanisms

M. Rathod, H. Franz, V. Beyersdorfer, M.-T. Wanuske, K. L. Fischer, P. Hanns, C. Stüdle, A. Zimmermann, K. Buczak, C. Schinner, V. Spindler

This study shows that DPM1 modulates desmosomal cohesion and epidermal differentiation via SERPINB5-dependent regulation of desmoplakin phosphorylation.

bioRxiv · Dec 28, 2022Cell Biology

Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade

C. Schinner, H. Franz, A. Zimmermann, M.-T. Wanuske, F. Geier, P. Pelczar, V. Lorenz, L. Xu, C. Stuedle, P. I. Maly, S. Kauferstein, B. M. Beckmann, G. M. Kuster, V. Spindler

This study shows that defective desmosomal adhesion causes arrhythmogenic cardiomyopathy through an integrin-αVβ6/TGF-β signaling cascade, leading to fibrosis and arrhythmias.

bioRxiv · Sep 2, 2021Cell Biology

Clustering of desmosomal cadherins by desmoplakin is essential for cell-cell adhesion

M.-T. Wanuske, D. Brantschen, C. Schinner, C. Stüdle, E. Walter, M. Hiermaier, F. Vielmuth, J. Waschke, V. Spindler

This study shows that desmoplakin is essential for clustering desmosomal cadherins and forming functional desmosomes, which are critical for cell-cell adhesion.

bioRxiv · Apr 6, 2020Cell Biology

The actin binding protein α-adducin modulates desmosomal turnover and plasticity

M. Hiermaier, F. Kliewe, C. Schinner, C. Stüdle, I. P. Maly, M.-T. Wanuske, V. Rötzer, N. Endlich, F. Vielmuth, J. Waschke, V. Spindler

This study shows that α-adducin modulates desmosome turnover and plasticity in response to mechanical stress by affecting the mobility of desmosomal molecules.

bioRxiv · Oct 1, 2019Cell Biology