Pharmacology & ToxicologybioRxivPreprint
Gene Deletion Studies Reveal A Critical Role For Prostamide/Prostaglandin F2α Synthase In Prostamide F2α Formation
J. A. Bertrand, D. F. Woodward, J. M. Sherwood…·D. Overby
This study deletes the PM/PGFS gene in mice and finds elevated intraocular pressure, suggesting PM/PGFS regulates prostanoid levels that affect eye pressure.
DOI 10.1101/2020.04.01.020768