Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection
R. Wang, A. Hume, M. L. Beermann, C. Simone-Roach, J. Lindstrom-Vautrin, J. Le Suer, J. Huang, J. Olejnik, C. Villacorta-Martin, E. Bullitt, A. Hinds, M. Ghaedi, R. Werder, K. Abo, A. Wilson, , F. J. Hawkins
This study uses iPSC-derived airway cells to model SARS-CoV-2 infection, showing multiciliated cells as primary targets and demonstrating antiviral responses to remdesivir and camostat methylate.
bioRxiv · Jul 6, 2021Cell Biology