Antigen-driven PD1+Tox+Eomes+ and PD1+Tox+BHLHE40+ synovial T lymphocytes regulate chronic inflammation in situ
P. Maschmeyer, G. A. Heinz, C. Skopnik, L. Lutter, A. Mazzoni, F. Heinrich, S. L. von Stuckrad, L. E. Wirth, C. L. Tran, R. Riedel, K. Lehmann, I. Sakwa, R. Cimaz, F. Giudici, M. A. Mall, , M.-F. Mashreghi
The paper identifies distinct subpopulations of synovial T lymphocytes in JIA patients using single-cell RNA-sequencing and shows their roles in regulating chronic inflammation.
bioRxiv · Dec 27, 2019 · PreprintImmunology