Author

C. Sparn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

W. Nickel· 2 shared A. Griffo· 1 shared A. Meyer· 1 shared A. Pichlmair· 1 shared A. Piras· 1 shared C. Urban· 1 shared D. Schweinoch· 1 shared E. Dimou· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

W. Nickel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanics of biomimetic free-standing lipid membranes: Insights on lipid chemistry and bilayer elasticity

A. Griffo, C. Sparn, F. Lolicato, F. Nolle, N. Khangholi, R. Seemann, J.-B. Fleury, M. Brinkmann, W. Nickel, H. Hahl

This study investigates the mechanical properties of biomimetic free-standing lipid membranes and identifies the influence of cholesterol and sphingomyelin on bilayer elasticity and adhesion.

bioRxiv · Aug 21, 2023 · PreprintBiophysics

High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

S. S. Burkart, D. Schweinoch, J. Frankish, C. Sparn, S. Wuest, C. Urban, A. Piras, A. Pichlmair, J. Willemsen, L. Kaderali, M. Binder

This study characterizes the kinetics of RIG-I signaling and develops a dynamic model to predict antiviral responses and virus-host interactions.

bioRxiv · Aug 5, 2022Immunology

Glypican-1 drives unconventional secretion of Fibroblast Growth Factor 2

C. Sparn, E. Dimou, A. Meyer, R. Saleppico, S. Wegehingel, M. Gerstner, S. Klaus, H. Ewers, W. Nickel

This study identifies Glypican-1 as the key factor driving unconventional secretion of FGF2, revealing its structural requirements and implications for tumor progression.

bioRxiv · Nov 11, 2021Biochemistry