A. Meyer

Experimental myositis: an optimised version of C-protein-induced myositis

This study optimises C-protein-induced myositis by immunising mice with a specific C-protein polypeptide, resulting in a reproducible and stable model of inflammatory myopathy with key pathological features.

LC3-associated phagocytosis is impaired in monocyte-derived macrophages from systemic sclerosis patients

Effects of water nutrient concentrations on stream macroinvertebrate community stoichiometry: a large-scale study

This study examines how water phosphorus and nitrogen levels affect stream macroinvertebrate community stoichiometry using a large dataset from France.

Efficient and sustained optogenetic control of sensory and cardiac systems

This paper introduces ChReef, an improved optogenetic tool with enhanced performance in sensory and cardiac systems, demonstrating its effectiveness in restoring visual and auditory function.

Redox Activated Substrates for Enhancing Activatable Cyclopropene Bioorthogonal Reactions

The paper identifies a cyclopropene-quinone pair that significantly enhances reactivity and demonstrates two activation mechanisms for bioorthogonal imaging.

The genetic legacy of the expansion of Bantu-speaking peoples in Africa

A genetic analysis of Bantu-speaking populations reveals serial founder events, local gene-flow, and a decline in genetic diversity with distance from western Africa.

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity.

This study identifies AMPKγ1 complex activity as a marker of health and longevity, showing its decline with age and association with frailty in humans and killifish.

H3.1Cys96 oxidation by mitochondrial ROS promotes chromatin remodeling, breast cancer progression to metastasis and multi-drug resistance

The paper shows that mitochondrial H2O2 oxidizes H3.1 at Cys96, promoting chromatin remodeling, breast cancer metastasis, and drug resistance.

New hypotheses of cell type diversity and novelty from comparative single cell and nuclei transcriptomics in echinoderms

This paper develops a gene expression atlas of the bat star using snRNA-seq and compares it to sea urchin embryos to reinterpret the evolution of cell types.

Endoplasmic reticulum oxidoreductin (ERO) provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics

The paper demonstrates that EROs maintain ER redox homeostasis by integrating reductive and oxidizing inputs during hypoxia and reductive stress.

Glypican-1 drives unconventional secretion of Fibroblast Growth Factor 2

This study identifies Glypican-1 as the key factor driving unconventional secretion of FGF2, revealing its structural requirements and implications for tumor progression.

Glutathione contributes to plant defense against parasitic cyst nematodes

This study shows that glutathione levels in Arabidopsis affect susceptibility to cyst nematodes by modulating redox balance and camalexin production.

Adaptive radiation and burst speciation of hillstream cyprinid fish in African river

This study identifies a riverine adaptive radiation in Ethiopian hillstream cyprinid fish, revealing rapid speciation and novel phenotypes through genomic and morphological analysis.

Photosynthetic activity triggers pH and NAD redox signatures across different plant cell compartments

The paper investigates how photosynthetic activity affects subcellular pH and NAD redox status in Arabidopsis cells using fluorescent biosensors.

The developmental and genetic architecture of the sexually selected male ornament of swordtails

The paper identifies genes associated with sword development in swordtail fish by analyzing transcriptional profiles and genetic mapping.

Autophagy in T cells from aged donors is maintained by spermidine, and correlates with function and vaccine responses

This study shows that spermidine maintains autophagy in aged human T cells, improving vaccine responses by enhancing IFN-gamma secretion and T cell function.

Parallel and non-parallel changes of the gut microbiota during trophic diversification in repeated young adaptive radiations of sympatric cichlid fish

The paper examines gut microbiota changes in young cichlid fish radiations, finding diet influences microbiota but no parallel changes across species.

ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology

The paper develops a fluorescent biosensor to measure MgATP2- dynamics in living plant cells, revealing tissue-specific gradients and stress responses in ATP homeostasis.