Author

L. Kaderali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Zitzmann· 2 shared M. Binder· 2 shared R. Bartenschlager· 2 shared A. Mueller· 1 shared A. Pichlmair· 1 shared A. Piras· 1 shared A. S. Perelson· 1 shared B. Bruegger· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Zitzmann

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivAug 5, 2022

High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

S. S. Burkart, D. Schweinoch, J. Frankish…·M. Binder

This study characterizes the kinetics of RIG-I signaling and develops a dynamic model to predict antiviral responses and virus-host interactions.

DOI 10.26508/lsa.202302059

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivJul 25, 2022

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

C. Zitzmann, C. Dächert, B. Schmid…·L. Kaderali

This paper develops a mathematical model of plus-strand RNA virus replication for HCV, DENV, and CVB3, identifying viral RNA translation and polyprotein cleavage as key targets for broad-spectrum antiviral strategies.

DOI 10.1371/journal.pcbi.1010423

statistical modeldrug response / drug discovery

𝕏 PostBluesky

MicrobiologybioRxivMay 10, 2021

Convergent use of phosphatidic acid for Hepatitis C virus and SARS-CoV-2 replication organelle formation

K. Tabata, V. Prasad, D. Paul…·R. Bartenschlager

This study identifies phosphatidic acid as critical for double membrane vesicle formation in HCV and SARS-CoV-2 replication, suggesting host-targeted PA synthesis inhibition as a therapeutic strategy.

DOI 10.1038/s41467-021-27511-1

humanexperimental assay

𝕏 PostBluesky