F. Lolicato

The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites

The paper identifies STARD3 as a sphingosine transporter at ER-lysosome contact sites, showing its role in sphingosine integration into ceramide.

Mechanics of biomimetic free-standing lipid membranes: Insights on lipid chemistry and bilayer elasticity

This study investigates the mechanical properties of biomimetic free-standing lipid membranes and identifies the influence of cholesterol and sphingomyelin on bilayer elasticity and adhesion.

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

This paper identifies C95-C95 disulfide-bridge-mediated FGF2 dimerization as essential for membrane translocation and oligomer formation, while C77 is involved in Na,K-ATPase binding.

The Ebola virus VP40 matrix undergoes endosomal disassembly essential for membrane fusion

This study shows that Ebola virus VP40 matrix disassembles in endosomes due to pH changes, facilitating membrane fusion and viral entry.

Cholesterol promotes both head group visibility and clustering of PI(4,5)P2 driving unconventional secretion of Fibroblast Growth Factor 2

This study shows cholesterol enhances FGF2 secretion by promoting PI(4,5)P2 clustering and membrane pore formation.

The role of alpha-helix on the structure-targeting drug design of amyloidogenic proteins

This study investigates how alpha-helix structure influences protein-lipid binding in amyloidogenic proteins, showing that helix content affects contact probability and supports a lipid-chaperon model for membrane interaction.

The α1 subunit of the Na,K-ATPase acts upstream of PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2 from tumor cells

This study identifies a direct interaction between FGF2 and the Na,K-ATPase α1 subunit, showing it facilitates FGF2 membrane translocation upstream of PI(4,5)P2.