Author

C. Stemberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Tschulik· 2 shared D. H. Busch· 2 shared K. Schober· 2 shared L. Germeroth· 2 shared M. Effenberger· 2 shared M. P. Poltorak· 2 shared S. P. Fraessle· 2 shared V. Cletiu· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

C. Tschulik

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Author profile →

2 papers

Recent·Most cited

Miniaturized CAR knocked onto CD3epsilon extends TCR function with CAR specificity under control of endogenous TCR signaling cascade

K. Manske, L. Dressler, S. P. Fraessle, M. Effenberger, C. Tschulik, V. Cletiu, E. Benke, M. Wagner, K. Schober, T. R. Mueller, D. H. Busch, C. Stemberger, L. Germeroth, M. P. Poltorak

This paper describes a method to miniaturize CAR T cells by integrating only the antigen-binding domain under the control of the endogenous TCR signaling cascade, preserving TCR function while enabling CAR specificity.

bioRxiv · May 30, 2023Bioengineering

Activation-inducible CAR expression enables precise control over engineered CAR T cell function

S. P. Fraessle, C. Tschulik, M. Effenberger, V. Cletiu, M. Gerget, K. Schober, D. H. Busch, L. Germeroth, C. Stemberger, M. P. Poltorak

This paper presents activation-inducible CAR T cells using CRISPR-mediated integration, enabling controlled CAR expression based on T cell activation status.

bioRxiv · Nov 8, 2022 · PreprintImmunology