Author

L. Dressler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Approach:benchmark study· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Repana· 2 shared F. D. Ciccarelli· 2 shared J. Nulsen· 2 shared M. Bortolomeazzi· 2 shared A. Acha-Sagredo· 1 shared A. Strange· 1 shared A. Tourna· 1 shared A. Yakovleva· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

D. Repana

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioengineeringbioRxivMay 30, 2023

Miniaturized CAR knocked onto CD3epsilon extends TCR function with CAR specificity under control of endogenous TCR signaling cascade

K. Manske, L. Dressler, S. P. Fraessle…·M. P. Poltorak

This paper describes a method to miniaturize CAR T cells by integrating only the antigen-binding domain under the control of the endogenous TCR signaling cascade, preserving TCR function while enabling CAR specificity.

DOI 10.1016/j.jim.2024.113617

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 31, 2021

Comparative assessment of genes driving cancer and somatic evolution.

L. Dressler, M. Bortolomeazzi, M. R. Keddar…·F. D. Ciccarelli

The paper assesses genes driving cancer and somatic evolution, revealing gaps in driver gene compendiums and identifying conserved genes that promote clonal expansion without malignancy.

DOI 10.1101/2021.08.31.458177

humanwhole-exome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivDec 1, 2018

The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens.

D. Repana, J. Nulsen, L. Dressler…·F. D. Ciccarelli

The paper curates a comprehensive list of 2,372 cancer-related genes from 275 publications, including sequencing screens of 119 cancer types, and provides annotations on their properties.

DOI 10.1186/s13059-018-1612-0

whole-exome sequencingwhole-genome sequencing

𝕏 PostBluesky