Author

C. Strell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:machine learning (classical)· 1 Assay:multiome· 1

Frequent Co-Authors

B. Bozoky· 2 shared M. Gerling· 2 shared A. L. Richardson· 1 shared A. Lomakin· 1 shared A. Shmatko· 1 shared A. Viljamaa· 1 shared A. Zacharouli· 1 shared B. Schmierer· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

B. Bozoky

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Author profile →

3 papers

Recent·Most cited

A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype

S. I. M. Söderqvist, A. Viljamaa, N. Geyer, C. Strell, N. Hekmati, J. Engstrand, E. Sparrelid, C. Salmen, R. L. Heuchel, A. Zacharouli, P. Ghorbani, S. Harrizi, Y. Hamidi, O. Khorosjutina, S. Milanova, , M. Gerling

This study identifies a distinctive PDAC niche in pancreatic lobules characterized by nascent stroma and classical tumor cell phenotype, highlighting the role of acinar-to-ductal metaplasia and microenvironmental factors in tumor progression.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology

Spatial genomics maps the structure, character and evolution of cancer clones

A. Lomakin, J. Svedlund, C. Strell, M. Gataric, A. Shmatko, J. S. Park, Y. S. Ju, S. Dentro, V. Kleshchevnikov, V. Vaskivskyi, T. Li, O. A. Bayraktar, L. Moore, S. Pinder, A. L. Richardson, , L. R. Yates

The paper develops a spatial genomics method to map cancer clone structure, character, and evolution across breast cancer progression stages.

bioRxiv · Apr 16, 2021 · PreprintCancer Biology

Basal-to-classical phenotypic switch of pancreatic cancer cells upon integration into the duodenal epithelium

B. Bozoky, C. Fernandez Moro, C. Strell, I. Ernberg, L. Szekely, M. Gerling, B. Bozoky

The paper shows that pancreatic cancer cells switch from a basal-like to classical subtype when integrating into the duodenal epithelium, linking microenvironmental cues to molecular subtype changes.

bioRxiv · Feb 1, 2021 · PreprintCancer Biology