Author

A. Lomakin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Gerstung· 2 shared M. Piel· 2 shared A. Bhargava· 1 shared A. L. Richardson· 1 shared A. Shmatko· 1 shared A.-M. P. Lennon-Dumenil· 1 shared C. Cattin· 1 shared C. J. Cattin· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

M. Gerstung

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Author profile →

4 papers

Recent·Most cited

Integrated combinatorial functional genomics and spatial transcriptomics of tumors decodes genotype to phenotype relationships

M. Breinig, A. Lomakin, E. Heidari, M. Ritter, G. Rukhovich, L. Boese, L. Butthof, L. Wendler-Link, H. Wiethoff, T. Poth, F. Sahm, P. Schirmacher, O. Stegle, M. Gerstung, D. Tschaharganeh

The paper introduces CHOCOLAT-G2P, a method integrating functional genomics and spatial transcriptomics to study genotype-phenotype relationships in tumors, revealing zonation patterns and epistasis in liver cancer.

bioRxiv · May 14, 2024 · PreprintCancer Biology

Advected percolation in the actomyosin cortex drives amoeboid cell motility

J. M. Garcia-Arcos, J. Ziegler, S. Grigolon, L. Reymond, G. Shajepal, C. J. Cattin, A. Lomakin, D. J. Mueller, V. Ruprecht, S. Wieser, R. Voituriez, M. Piel

The paper identifies advected percolation as a mechanism driving amoeboid cell motility by analyzing actin cortex dynamics in motile blebs.

bioRxiv · Jul 14, 2022 · PreprintBiophysics

Spatial genomics maps the structure, character and evolution of cancer clones

A. Lomakin, J. Svedlund, C. Strell, M. Gataric, A. Shmatko, J. S. Park, Y. S. Ju, S. Dentro, V. Kleshchevnikov, V. Vaskivskyi, T. Li, O. A. Bayraktar, L. Moore, S. Pinder, A. L. Richardson, , L. R. Yates

The paper develops a spatial genomics method to map cancer clone structure, character, and evolution across breast cancer progression stages.

bioRxiv · Apr 16, 2021 · PreprintCancer Biology

The nucleus acts as a ruler tailoring cell responses to spatial constraints

A. Lomakin, C. Cattin, D. Cuvelier, Z. Alraies, M. Molina, G. Nader, N. Srivastava, J.-M. Garcia Arcos, I. Zhitnyak, A. Bhargava, M. K. Driscoll, E. S. Welf, R. P. Fiolka, R. Petrie, N. Manel, , M. Piel

The paper shows that the nucleus acts as a ruler by triggering contractile responses when confined, influencing cell migration and processes like cancer invasion and immune responses.

bioRxiv · Dec 5, 2019Cell Biology