Author

B. Schmierer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. C. Iuga· 1 shared A. Califano· 1 shared A. Chaban· 1 shared A. Curiel Garcia· 1 shared A. Griffin· 1 shared A. L. E. Wang· 1 shared A. Viljamaa· 1 shared A. Zacharouli· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. C. Iuga

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis

M. R. Babu Sait, L. H. Jachmann, M. Milivojevic, C. Llorente-Saez, S. Dhanjal, F. Schumacher, S. Henriksson, N. V. Gayathri Vegesna, A. Chaban, P. Mohanty, M. Ölander, S. Muraleedharan, S. Farmand Azadeh, B. Kleuser, B. Schmierer, B. S. Sixt

The paper identifies CpoS as a key effector for maintaining Chlamydia trachomatis vacuole integrity by regulating sphingolipid supply and shows that disrupting this pathway can clear infection without harming host cells.

PLOS Biology · Aug 12, 2025Peer-reviewedMicrobiology

A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype

S. I. M. Söderqvist, A. Viljamaa, N. Geyer, C. Strell, N. Hekmati, J. Engstrand, E. Sparrelid, C. Salmen, R. L. Heuchel, A. Zacharouli, P. Ghorbani, S. Harrizi, Y. Hamidi, O. Khorosjutina, S. Milanova, , M. Gerling

This study identifies a distinctive PDAC niche in pancreatic lobules characterized by nascent stroma and classical tumor cell phenotype, highlighting the role of acinar-to-ductal metaplasia and microenvironmental factors in tumor progression.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology

Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer

P. Laise, M. Turunen, A. Curiel Garcia, L. Tomassoni, C. Maurer, E. Elyada, B. Schmierer, J. Worley, J. Kesner, X. Tan, E. Calvo Fernandez, K. Wong, U. Wasko, S. Tagore, A. L. E. Wang, , A. Califano

The paper identifies three developmental lineages in pancreatic cancer driven by master regulators and shows their association with MAPK activity and therapeutic vulnerabilities.

bioRxiv · Oct 27, 2020 · PreprintCancer Biology

TGF-β family ligands exhibit distinct signaling dynamics that are driven by receptor localization

D. S. J. Miller, B. Schmierer, C. S. Hill

The paper shows that TGF-β family ligands have distinct signaling dynamics due to differences in receptor localization and internalization, driven by ligand-receptor affinity.

bioRxiv · Mar 1, 2019Cell Biology