Author

C. V. Pecot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. E. D. Van Swearingen· 3 shared S. H. Azam· 2 shared A. C. Dudley· 1 shared A. D. Cox· 1 shared A. Porrello· 1 shared A. V. Kabanov· 1 shared A. Y. Feng· 1 shared B. Papke· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

A. E. D. Van Swearingen

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4 papers

Recent·Most cited

Periostin+ stromal cells guide lymphovascular invasion by cancer cells

J. L. Null, D. J. Kim, J. V. McCann, P. Pramoonjago, J. W. Fox, P. Kumar, L. Edatt, C. V. Pecot, A. C. Dudley

This study identifies periostin-expressing cancer-associated fibroblasts that promote lymphatic metastasis by remodeling the extracellular matrix and facilitating cancer cell invasion.

Cancer Research · May 19, 2023Peer-reviewedCancer Biology

Silencing of oncogenic KRAS by mutant-selective small interfering RNA

B. Papke, S. H. Azam, A. Y. Feng, A. E. D. Van Swearingen, C. Gutierrez-Ford, P. S. Pallan, M. Egli, A. D. Cox, C. J. Der, C. V. Pecot

This study develops a mutant-selective siRNA, EFTX-D1, that targets KRAS mutations in codons 12 and 13, reducing mutant KRAS expression and impairing cancer cell proliferation.

bioRxiv · Oct 8, 2020Cancer Biology

Snord67 promotes lymph node metastasis and regulates U6-mediated alternative splicing in breast cancer

Y. L. Chao, Y. Zhu, H. J. Wiedner, Y.-H. Tsai, L. Wilkinson, A. Porrello, A. E. D. Van Swearingen, L. A. Carey, J. Giudice, C. L. Holley, C. V. Pecot

This study identifies Snord67 as a regulator of lymph node metastasis in breast cancer by modulating U6-mediated alternative splicing.

bioRxiv · Aug 28, 2020 · PreprintCancer Biology

High Capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of Lung Adenocarcinoma

N. Vinod, D. Hwang, S. H. Azam, A. E. D. Van Swearingen, E. Wayne, S. C. Fussell, M. Sokolsky-Papkov, C. V. Pecot, A. V. Kabanov

This study shows that a novel nanomicellar formulation of Resiquimod extends survival in a metastatic lung adenocarcinoma model more effectively than chemotherapy and anti-PD1 therapy.

bioRxiv · Dec 12, 2019Pharmacology & Toxicology