Functional evaluation of microdissected tumor 'cuboids': a microscale ex vivo cancer model that retains a complex tumor microenvironment
L. F. Horowitz, R. A. Rodriguez-Mias, M. Chang, S. Zhu, Y. Tang, A. Locke, N. R. Gottshall, I. Stepanov, C. Stiles, M. Yeung, T. N. Nguyen, E. J. Lockhart, C. Ahls, E. Wayne, W. Wei, , A. Folch
The paper develops a microscale ex vivo cancer model using tumor cuboids that retain a complex tumor microenvironment, enabling drug and immunotherapy testing.
bioRxiv · Mar 22, 2024 · PreprintCancer Biology