MicrobiologybioRxiv
Hepatitis C virus infection is inhibited by a non-canonical antiviral signaling pathway targeted by NS3-NS4A
C. Vazquez, C. Y. Tan, S. M. Horner
This paper identifies a non-canonical antiviral signaling pathway involving Riplet and IRF3 that is inhibited by the HCV NS3-NS4A protease, revealing a new mechanism of immune evasion.
DOI 10.1128/jvi.00725-19