RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes
J. T. Walker, D. C. Saunders, V. Rai, C. Dai, P. Orchard, A. L. Hopkirk, C. V. Reihsmann, Y. Tao, S. Fan, S. Shrestha, A. Varshney, J. J. Wright, Y. D. Pettway, C. Ventresca, S. Agarwala, , M. Brissova
This study identifies RFX6 as a key regulator of β cell dysfunction in early type 2 diabetes through multi-omics analysis of human pancreatic tissue.
bioRxiv · Dec 16, 2021Cell Biology