A. Varshney

A novel glideosome-associated protein S14 coordinates sporozoite gliding motility and infectivity in mosquito and mammalian hosts

Anti-oxidant Response of Lipidom Modulates Lipid Metabolism in Caenorhabditis elegans and in OxLDL-Induced Human Macrophages by Tuning Inflammatory Mediators

This study evaluates the anti-oxidant and lipid-lowering effects of Lipidom in human macrophages and C. elegans, showing reduced inflammation, oxidative stress, and lipid accumulation.

RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes

This study identifies RFX6 as a key regulator of β cell dysfunction in early type 2 diabetes through multi-omics analysis of human pancreatic tissue.

Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration

This paper identifies fluoxetine as a potential repurposed drug for dry AMD by showing it inhibits NLRP3-ASC inflammasome activation and reduces RPE degeneration in mice, supported by epidemiological data.

Systems Biology under heat stress in Indian Cattle

This study compares gene expression under heat stress in two Indian cattle breeds, finding Tharparkar better adapts through upregulated stress response and antioxidant genes.

Bright split red fluorescent proteins with enhanced complementation efficiency for the tagging of endogenous proteins and visualization of synapses

The paper improves split fluorescent proteins for better brightness and develops a new synaptic marker for visualizing synapses in living animals.