Author

C. Watzl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. Claus· 2 shared A. Braun· 1 shared A. Cid-Arregui· 1 shared A. Graczyk-Jarzynka· 1 shared A. Kayhan· 1 shared A. Kusowska· 1 shared C. Bade-Doding· 1 shared C. Liesche· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

M. Claus

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infection

M. Z. Hasan, M. Claus, N. Kruger, S. Reusing, E. Gall, C. Bade-Doding, A. Braun, C. Watzl, M. Uhrberg, L. Walter

This study shows SARS-CoV-2 increases HLA-E expression via spike protein processing, modulating NK cell function by affecting canonical and adaptive NK cells differently during acute infection.

bioRxiv · Mar 4, 2024Immunology

Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin

M. Winiarska, J. Domagala, T. M. Grzywa, I. Baranowska, A. Kusowska, K. Fidyt, K. Marhelava, Z. Pilch, A. Graczyk-Jarzynka, L. Picard, K. Jastrzebski, M. Granica, M. Justyniarska, D. Urlaub, M. Bobrowicz, , C. Watzl

This study shows ammonia reduces NK cell antitumor activity by decreasing mature perforin levels in the tumor microenvironment.

bioRxiv · Nov 20, 2023 · PreprintCancer Biology

Activating NK- receptors, homing selectins and inhibitory Siglecs recognize EBOLA-GP and HPV-L1NK

M. Jarahian, K. Marstaller, H. Wurmbäck, N. Banna, R. Ahani, M. H. Etemadzadeh, L. K. Boller, A. Kayhan, A. Cid-Arregui, M. R. Berger, F. Momburg, C. Watzl

This study identifies NK receptors, selectins, and Siglecs as receptors for Ebola-GP and HPV-L1, showing their role in virus recognition and immune escape.

bioRxiv · Jul 24, 2020 · PreprintImmunology

Single-fluorescent protein reporters allow parallel quantification of NK cell-mediated granzyme and caspase activities in single target cells

C. Liesche, P. Sauer, M. Claus, R. Eils, J. Beaudouin, C. Watzl

The paper develops single-fluorescent protein reporters to measure granzyme and caspase activities in individual target cells, revealing a 6-minute delay between granzyme B and caspase-3 activation.

bioRxiv · May 22, 2018Immunology