Author

C. Liesche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. Beaudouin· 2 shared R. Eils· 2 shared A. Fraudeau· 1 shared B. Gallet· 1 shared C. Moriscot· 1 shared C. Watzl· 1 shared E. Kandiah· 1 shared F. Barras· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

J. Beaudouin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane

J. Felix, L. Bumba, C. Liesche, A. Fraudeau, F. Rebeille, J. El Khoury, K. Huard, B. Gallet, C. Moriscot, J.-P. Kleman, Y. Duhoo, M. Jessop, E. Kandiah, F. Barras, J. Jouhet, I. Gutsche

This study identifies RavA and ViaA as modulators of E. coli aminoglycoside sensitivity through lipid interactions affecting membrane morphology and antibiotic resistance.

bioRxiv · Feb 6, 2022Microbiology

Single-fluorescent protein reporters allow parallel quantification of NK cell-mediated granzyme and caspase activities in single target cells

C. Liesche, P. Sauer, M. Claus, R. Eils, J. Beaudouin, C. Watzl

The paper develops single-fluorescent protein reporters to measure granzyme and caspase activities in individual target cells, revealing a 6-minute delay between granzyme B and caspase-3 activation.

bioRxiv · May 22, 2018Immunology

CD95 receptor activation by ligand-induced trimerization is independent of its partial pre-ligand assembly

C. Liesche, J. Berndt, F. Fricke, S. Aschenbrenner, M. Heilemann, R. Eils, J. Beaudouin

This paper investigates how CD95 receptor activation occurs through ligand-induced trimerization, showing that receptor multimerization follows ligand binding while FADD recruitment is delayed, and that soluble CD95L is a poor inducer of apoptosis due to inefficient FADD recruitment.

bioRxiv · Apr 2, 2018 · PreprintCell Biology