Author

C. Werbrich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

A. D. Prabakaran· 3 shared H. B. Durumutla· 3 shared H. Latimer· 3 shared K. McFarland· 3 shared K. Piczer· 3 shared M. Quattrocelli· 3 shared F. E. A. Soussi· 2 shared K. Miz· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

A. D. Prabakaran

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3 papers

Recent·Most cited

The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.

A. D. Prabakaran, H.-J. Chung, K. McFarland, T. Govindarajan, F. E. A. Soussi, H. B. Durumutla, C. Villa, K. Piczer, H. Latimer, C. Werbrich, O. Akinborewa, R. Horning, M. Quattrocelli

This study identifies Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle, using a human SNP rs6190 in mice and human datasets.

bioRxiv · Mar 28, 2024 · PreprintPhysiology

Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism

F. El Abdellaoui-Soussi, H. B. Durumutla, H. Latimer, A. D. Prabakaran, K. McFarland, K. Miz, K. Piczer, C. Werbrich, M. K. Jain, S. M. Haldar, M. Quattrocelli

This study identifies the cardiomyocyte-specific GR-KLF15 axis as a circadian-regulated regulator of glucose metabolism, showing that timed glucocorticoid administration improves cardiac function in diabetic mice.

bioRxiv · Dec 18, 2023 · PreprintPhysiology

Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation

A. D. Prabakaran, K. McFarland, K. Miz, H. B. Durumutla, F. E. A. Soussi, K. Piczer, H. Latimer, C. Werbrich, N. S. Blair, D. P. Millay, B. Prideaux, B. N. Finck, M. Quattrocelli

This study shows that intermittent glucocorticoid treatment rescues both energy and mass in aging-related sarcopenia via the PGC1alpha-Lipin1 pathway in muscle cells.

bioRxiv · Oct 16, 2023 · PreprintPhysiology