MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
O. El Bounkari, C. Zan, J. Wagner, E. Bugar, P. Bourilhon, C. Kontos, M. Zarwel, D. Sinitski, J. Milic, Y. Jansen, W. Kempf, L. Maegdefessel, A. Hoffmann, M. Brandhofer, R. Bucala, , J. Bernhagen
This study identifies MIF-2 as an atherogenic chemokine that promotes atherosclerosis and hepatic lipogenesis by acting through CXCR4 and SREBP pathways.
bioRxiv · Dec 28, 2021 · PreprintImmunology