Author

R. Bucala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Lauko· 2 shared A. Rabljenovic· 2 shared B. Otvos· 2 shared G. Roversi· 2 shared J. Lathia· 2 shared L. Leng· 2 shared T. Alban· 2 shared A. Baeza Garcia· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Lauko

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The MIF SNP rs755622 is a germline determinant of tumor immune activation in Glioblastoma

T. Alban, M. M. Grabowski, B. Otvos, D. B. Watson, A. Zalavadia, V. Makarav, K. M. Troike, M. McGraw, A. Rabljenovic, A. Lauko, C. K. A. Neumann, G. Roversi, K. Waite, G. Cioffi, N. Patil, , J. Lathia

The paper identifies a germline SNP, rs755622, associated with increased leukocyte infiltration in glioblastoma and links it to lactotransferrin expression as a potential biomarker for immune activation.

bioRxiv · Mar 7, 2022 · PreprintCancer Biology

MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

O. El Bounkari, C. Zan, J. Wagner, E. Bugar, P. Bourilhon, C. Kontos, M. Zarwel, D. Sinitski, J. Milic, Y. Jansen, W. Kempf, L. Maegdefessel, A. Hoffmann, M. Brandhofer, R. Bucala, , J. Bernhagen

This study identifies MIF-2 as an atherogenic chemokine that promotes atherosclerosis and hepatic lipogenesis by acting through CXCR4 and SREBP pathways.

bioRxiv · Dec 28, 2021 · PreprintImmunology

Suppression of Plasmodium MIF-CD74 Signaling Protects Against Severe Malaria

A. Baeza Garcia, E. Siu, X. Du, L. Leng, B. Franke-Fayard, C. J. Janse, S. Howland, L. Renia, E. Lolis, R. Bucala

This study shows that blocking Plasmodium MIF-CD74 signaling protects against experimental cerebral malaria by preventing antigen presentation to CD8+ T cells.

bioRxiv · Feb 14, 2021Microbiology

Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression

T. Alban, D. Bayik, B. Otvos, A. Rabljenovic, L. Leng, L. Jia-shiun, G. Roversi, A. Lauko, A. Momin, A. M. Mohammadi, D. M. Peereboom, M. S. Ahluwalia, K. Matsuda, K. Yun, R. Bucala, , J. Lathia

This study identifies differential MIF receptor expression in GBM MDSC subsets and shows targeting M-MDSCs with ibudilast reduces immune suppression.

bioRxiv · Dec 19, 2019Immunology