C.-C. Cheng

Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

This study identifies the STAT3/AMPK/PFKL axis in liver cancer, showing how it promotes glycolysis and tumor growth through stabilization of PFKL and RPIA in glycolytic bodies.

A Weakly Supervised U-Net Model for Precise Whole Brain Immunolabeled Cell Detection

The paper develops a weakly supervised U-Net model for precise segmentation of whole brain immunolabeled cell signals, revealing distinct neural activity maps related to social motivations.

DDR1-INDUCED NEUTROPHIL EXTRACELLULAR TRAPS DRIVE PANCREATIC CANCER METASTASIS

This study shows DDR1 signaling in pancreatic cancer cells promotes metastasis by inducing CXCL5 production, which recruits neutrophils to form extracellular traps that facilitate cancer cell invasion.

Sperm-specific COX6B2 Enhances Oxidative Phosphorylation, Proliferation, and Survival in Lung Adenocarcinoma

The paper identifies COX6B2 as a sperm-specific gene that enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma by hijacking sperm motility metabolism.

The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGF-beta; signaling in triple-negative breast cancer

The paper identifies ZNF165 as a SMAD3 cofactor that enhances TGF-beta signaling in triple-negative breast cancer, promoting tumor growth and survival.