Author

C.-e. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

Z. Tang· 2 shared K.-P. Wu· 1 shared T. Cholko· 1 shared T. I. Hung· 1 shared W. Chen· 1 shared W.-L. Lu· 1 shared Y.-J. Hsieh· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Z. Tang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

What Strengthens Protein-Protein Interactions: Analysis and Applications of Residue Correlation Networks

T. I. Hung, Y.-J. Hsieh, W.-L. Lu, K.-P. Wu, C.-e. Chang

The paper identifies critical residues in protein-protein interactions through residue correlation networks and demonstrates a method to design high-affinity protein binders with improved selectivity and potency.

bioRxiv · Mar 15, 2023Biophysics

Binding Thermodynamics and Kinetics Calculations Using Chemical Host and Guest: A Comprehensive Picture of Molecular Recognition

Z. Tang, C.-e. Chang

This study computes binding thermodynamics and kinetics of guest molecules with β-cyclodextrin using MD simulations and force fields, showing discrepancies in driving forces between GAFF-CD and q4MD-CD.

bioRxiv · Aug 24, 2017Biophysics

A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery

W. Chen, Z. Tang, T. Cholko, C.-e. Chang

This study uses molecular dynamics simulations to analyze CDK8/CycC conformational flexibility and ligand binding, identifying key interactions that could inform drug discovery.

bioRxiv · Jul 28, 2017Biophysics