Modulation of adenine phosphoribosyltransferase-mediated salvage to promote diabetic wound healing
G.-H. Young, J.-T. Lin, Y.-F. Cheng, C.-F. Ho, Q.-Y. Kuok, R.-C. Hsu, W.-R. Liao, C.-C. Chen, H.-M. Chen
This study shows that adenine supplementation enhances ATP levels and accelerates wound healing in diabetic mice by modulating APRT-mediated purine salvage.
bioRxiv · Apr 8, 2020 · PreprintPathology