NeurosciencebioRxivPreprint
Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis
Colton R Lysaker, Chelsea N. Johnson, Vivien Csikós…·Heather Wilkins
This study identifies APOE4-dependent metabolic changes in brain cells, showing increased glycolysis and mitochondrial dysfunction in neurons and astrocytes.
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