Molecular BiologybioRxivPreprint
The Rtf1/Prf1-dependent histone modification axis and Rpb1 C-terminal domain phosphorylation counteract multi-drug resistance in fission yeast
Jennifer J. Chen, Calvin Moy, Viviane Pagé…·Jason C. Tanny
The paper identifies a gene regulatory function of the Rtf1-H2Bub1-H3K4me axis and Rpb1 CTD in controlling fungal drug tolerance by linking them to resistance against hydroxyurea and azole antifungals.
DOI 10.1101/2023.11.24.568120