Mitochondrial transfer mediates metabolic communication between beta cells and islet macrophages
Lauar de Brito Monteiro, Anne‐Sophie Archambault, Paula Ma, Galina Soukhatcheva, Derek Dai, Jane Velghe, Dorian Izerable, Majid Mojibian, Annette E. Patterson, Ramon I. Klein Geltink, Cameron Bruce Verchere
The paper shows beta cells transfer mitochondria to islet macrophages, enhancing their protein synthesis and altering gene expression, suggesting a new communication mechanism in islet homeostasis.
bioRxiv · Sep 3, 2026 · PreprintCell Biology