Author
Albert Einstein College of Medicine
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Ashwin Ragupathi, Heba Zuhair Abid, Yun Chen…·Dong Zhang
This study shows DNA2 and FANCM function in distinct pathways to suppress replication stress at ALT telomeres, with their combined depletion causing synthetic lethality in ALT+ cancers.
Anthony Fernandez, Tingting Zhou, Robert Steven Esworthy…·Binghui Shen
The paper shows DNA2 and MSH2 work together to remove G4 structures at telomeres, preventing replication issues and telomere instability.
Manrose Singh, Kaitlin Raseley, Alexis M. Perez…·Dong Zhang
This study uses a CRISPR-dCas9 model to investigate the BFB cycle, revealing increased DNA damage, chromosome fusions, and involvement of DNA repair pathways in ITCB formation.
Sana Ahmed‐Seghir, Manisha Jalan, Helen E. Grimsley…·Simon N. Powell
The paper shows that a single replication fork barrier activates a local ATR-dependent checkpoint response in human cells, leading to localized DNA damage signaling without affecting global replication.
Arijita Chakraborty, Piroon Jenjaroenpun, Jing Li…·Wenyi Feng
This study shows FMRP prevents chromosome fragility by reducing R-loop formation and identifies novel FXS-susceptible genes.
Yannick Delpu, Thomas McNamara, Patrick T. Griffin…·Mamta Tahiliani
The paper shows hypomethylation of Satellite 2 sequences impairs DNA replication, leading to chromosomal rearrangements and genomic instability.