Cell BiologyCell Communication and SignalingPeer-reviewed
M1-derived extracellular vesicles polarize recipient macrophages into M2 and alter skeletal muscle homeostasis in a hyper-glucose environment
Stefano Tacconi, Francesco Vari, Carolina Sbarigia…·Luciana Dini
This study shows that high-glucose-treated macrophage-derived extracellular vesicles polarize recipient macrophages into M2 and alter skeletal muscle homeostasis, inducing insulin resistance or hyper-phosphorylation depending on glucose concentration.
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