NeurosciencebioRxivPreprint
A robust evaluation of TDP-43, poly GP, cellular pathology, and behavior in a AAV-C9ORF72 (G4C2)66 mouse model
Emily G. Thompson, Olivia Spead, Sigvard Åkerman…·Jeffrey D. Rothstein
This study evaluates a mouse model of C9-ALS/FTD, finding it robust for molecular mechanisms but not for neurodegeneration and motor deficits.
DOI 10.1101/2024.08.27.607409