Developmental BiologybioRxivPreprint
Aberrant extracellular matrix and cardiac development in models lacking the PR-DUB component ASXL3
BT McGrath, Yao-Chang Tsan, Shachi Salvi…·Stephanie L. Bielas
This study investigates the role of ASXL3 in cardiac development using mouse and human models, finding that its loss leads to cardiac abnormalities and extracellular matrix dysfunction.