Developmental BiologybioRxivPreprint
The transcription factor OCT6 promotes the dissolution of the naive pluripotent state by repressing Nanog and activating a formative state gene regulatory network.
Ariel Waisman, Federico Sevlever, Denisse Saulnier…·Santiago Miriuka
This paper identifies OCT6 as a key transcription factor promoting the transition from naive to formative pluripotency by repressing Nanog and activating formative gene regulatory networks in mouse embryonic stem cells.
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