APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology
Kristine M. Tran, Nellie E. Kwang, Claire Ann Butler…·Kim N. Green
The paper investigates how the APOE Christchurch variant affects microglial responses to amyloid and tau pathology in mouse models, finding it enhances plaque-related responses but suppresses tau-related inflammation.