Cancer BiologybioRxivPreprint
JNK pathway suppression drives resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer
Sarah Alexandrou, Christine S Lee, Kristine J. Fernandez…·Catherine Elizabeth Caldon
This study identifies JNK pathway suppression as a driver of resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer, with implications for patient stratification.
DOI 10.1101/2025.01.08.631992