GeneticseLifePeer-reviewed
Use of a ubiquitous gene-editing tool in budding yeast causes off-target repression of neighboring gene protein synthesis
Emily Nicole Powers, Charlene Chan, Ella Doron‐Mandel…·Gloria Ann Brar
The paper shows that deleting DBP1 in yeast using a selection cassette causes off-target repression of MRP51 through a LUTI-based mechanism, leading to mutant phenotypes.
20 citations