Cell BiologyNature CommunicationsPeer-reviewed
A cyclin-polarity feedback network ensures healthy cell proliferation
Landry Peyran, Charles Lefranc, Steven P. Gygi…·Derek McCusker
The paper identifies a feedback mechanism where G1-cyclin-Cdc28Cdk1 corrects polarity errors during cell cycle progression in budding yeast, but can lead to multinucleate cells if defects are irreparable.
DOI 10.1038/s41467-026-74596-7