Author

Che Woodson

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metagenomics· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anitha SundararajaniD· 3 shared Ashley M. SidebottomiD· 3 shared Emma McSpadden· 3 shared Eric G. PameriD· 3 shared Huaiying LiniD· 3 shared Cody G. ColeiD· 2 shared David MoraniD· 2 shared Mary McMilliniD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Anitha SundararajanORCID

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3 papers

Recent·Most cited

Lantibiotic-producing bacteria impact microbiome resilience and colonization resistance

Cody G. Cole, Zhenrun Jerry Zhang, Shravan R. Dommaraju, Qiwen Dong, Rosemary L. Pope, Sophie S Son, Emma McSpadden, Che Woodson, Huaiying Lin, Nicholas P. Dylla, Ashley M. Sidebottom, Anitha Sundararajan, Douglas A. Mitchell, Eric G. Pamer

This study shows lantibiotic-producing bacteria reduce microbiome resilience and increase susceptibility to infections after antibiotic treatment.

Cell Host & Microbe · Dec 1, 2025Peer-reviewedMicrobiology

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain

Qiwen Dong, Stephen Harper, Emma McSpadden, Sophie S Son, Marie-Maude Allen, Huaiying Lin, Rita C. Smith, Carolyn K. Metcalfe, Victoria Burgo, Che Woodson, Anitha Sundararajan, Amber R. Rose, Mary McMillin, David Moran, Jessica Little, , Eric G. Pamer

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

Cell Host & Microbe · Nov 27, 2024Peer-reviewedMicrobiology

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Zhenrun J. Zhang, Cody G. Cole, Michael J. Coyne, Huaiying Lin, Nicholas Dylla, Rita C. Smith, Téa E. Pappas, Shannon A. Townson, Nina Laliwala, Emily Waligurski, Ramanujam Ramaswamy, Che Woodson, Victoria Burgo, Jessica C. Little, David Moran, , Laurie E. Comstock

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

bioRxiv · Mar 8, 2024Microbiology