Anitha Sundararajan

The paper analyzes the gut microbiome of South Asian communities to show that urbanization impacts microbiomes differently across communities, with geography and culture playing a stronger role than lifestyle.

This study shows lantibiotic-producing bacteria reduce microbiome resilience and increase susceptibility to infections after antibiotic treatment.

The paper identifies a novel gut bacterial pathway for steroid hormone metabolism and shows its impact on drug efficacy in Crohn's disease.

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

The paper shows that a mobile genetic element inverts the antagonistic behavior of Bacteroides fragilis by disabling its native system and enhancing fitness through a new weapon.

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

The paper characterizes six gut-derived nisin-like lantibiotics, evaluates their antimicrobial activity against pathogens and commensals, and identifies key residues affecting their activity.

The paper describes bacterial strains in the human gut using a statistical model based on their evolutionary history to predict metabolic phenotypes and engineer consortia.