Author

Cheng Cheng

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Alejandro A. Espinosa PereziD· 1 shared Amy R. Henry· 1 shared Andrea BijuiD· 1 shared Annika RössleriD· 1 shared Audrey S. Carson· 1 shared Baoshan ZhangiD· 1 shared Bette KorberiD· 1 shared Brooke L. FridleyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Alejandro A. Espinosa PerezORCID

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Author profile →

2 papers

Recent·Most cited

BiNVaST: niche boundary-preserving and synthetic data-guided variational autoencoders for concordant inference across high-resolution spatial transcriptomic platforms

Jingxuan Zhang, Lei Li, Limeng Liu, Brooke L. Fridley, Cheng Cheng, Jasmine Plummer, Gang Wu, Jason Chiang, Qian Li

BiNVaST improves cell typing across spatial transcriptomic platforms by generating synthetic data that preserves niche boundaries and integrates molecular and spatial information.

bioRxiv · Oct 21, 2026 · PreprintBioinformatics

Vaccine Elicitation of HIV-1 Neutralizing Antibodies Against Both V2 Apex and Fusion Peptide in Rhesus Macaques

Hongying Duan, Joseph P. Nkolola, Shuishu Wang, Jayeshbhai Chaudhari, I‐Ting Teng, Christy L. Lavine, Danealle K. Parchment, George S. Sellers, Krisha McKee, Sijy J. O'Dell, Misook Choe, Haijuan Du, Baoshan Zhang, Alejandro A. Espinosa Perez, Annika Rössler, , Dan H. Barouch

This study designs a dual-epitope vaccine targeting HIV-1 Env's fusion peptide and V2 apex, showing it elicits neutralizing antibodies against both sites in rhesus macaques.

Cell Reports · Jan 29, 2026Peer-reviewedImmunology