BiochemistrybioRxivPreprint
A peptide-centric local stability assay to unveil protein targets of diverse ligands
Kejia Li, Shijie Chen, Keyun Wang…·Mingliang Ye
This paper introduces PELSA, a peptide-centric local stability assay that identifies ligand-binding regions across the proteome with high sensitivity and without ligand modification.
DOI 10.1101/2023.10.17.562693