ImmunologybioRxivPreprint
LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3
Ningbo Zheng, Roshni Jaffery, Ashley M. Guerrero…·Weiyi Peng
This study shows that the LRRK2 G2019S mutation impairs Th9 and Treg cell differentiation while enhancing Th2 differentiation through JAK/STAT3 signaling in T cells.
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