Molecular BiologyThe EMBO JournalPeer-reviewed
Master transcription factor binding sites constitute the core of early replication control elements
Jesse L. Turner, Laura Hinojosa-Gonzalez, Takayo Sasaki…·David M. Gilbert
The paper identifies subERCEs as master transcription factor binding sites that drive early replication timing and transcription in mESCs, functioning as both enhancers and structural chromatin organizers.