Molecular BiologyFrontiers in ImmunologyPeer-reviewed
High dose IFN-β activates GAF to enhance expression of ISGF3 target genes in epithelial cells
Kensei Kishimoto, Catera L. Wilder, Justin Buchanan…·Quen J. Cheng
The paper shows that high-dose IFN-β activates both ISGF3 and GAF in epithelial cells, with GAF enhancing ISGF3 target gene expression through co-localization and chromosome looping.
5 citations